After losing almost all their members the Tobita Crush Gear club is facing extinction. Kouya who dreams of being a Crush Gear Fighting Champion doesn't want to see the club become extinct and will do whatever he can to keep the club running and become a Cush Gear Champion.

Qin Lie has pulled up twelve spiritual columns, but the war between the Evil Clan and many tribues is imminent. However, at the most critical moment, the appearance of Li Mu in Tianjian Mountain prevented things from going in the worst direction.

Yachiyo Inugami, a cat-loving extrovert, and Suzu Nekoyama, a dog-loving introvert, are unexpectedly cast into a relationship on a day like any other. The pair find themselves drawn together through an inexplicable attraction of their opposite personalities. As they quickly begin to understand one another, Inugami's hardened resolve to gain Nekoyama's favor only leads to frenzied responses. Soon after their momentous union, the two begin to spend more time with one another, growing closer all the while. Their combined antics gain the attention of the mousy Mikine Nezu, a classmate of Inugami, and soon they join the "biology" club. There, they meet Ushikawa Ukiji, a passive, cow-like upperclassmen. Nezu and Nekoyama soon begin to build upon their relationship and a game of cat and mouse soon begins. Wild, explosive, and vibrant, Inugami-san to Nekoyama-san tells the comedic tale of two high school girls and their less-than-normal relationship. [Written by MAL Rewrite]

Special episodes included in the Blu-ray and DVD boxes of Kuma Miko.