Based on the long cherished, classic Japanese novel Nanso Satomi Hakkenden by Bakin Kyokutei Takizawa (1767), a modified version of it was made into animation. Taking place in the future, during this time wars were occuring in heaven, mostly for possession between the eight moons created by the savior Fuse that surrounded God's land. When the war ended, there was only one ruling family - that of the Oowaris, and the remaining son gained control of all the moons of heaven, except for one. Meiten, the moon of the pope, where people refrained from war and were therefore out of it's terms. Eight people. Each from one of the eight moons. Each possessing one of the jewels - the elements that compose Earth. They are those who are destined to become saviors of humanity. All of them have sacrificed for these jewels, and are determined to complete their duty to Queen Fuse who entrusted these to them. When the mad emperor Kai threatens to revive a ghost who wants to prevent the restoration of Earth, these eight must battle using the powers given by their jewels in order to create Earth and defeat those who want to prevent it. So they all go to Kusanagi, the ship in the center of God's land. They must gather the jewels in the key called Yatsufusa at Kusanagi's center, in order to create Earth.

A mysterious organization known as Panther Claw make their presence known by terrorizing Tokyo and giving the cops a run for their money. Police are further baffled by the appearance of a lone cosplaying vigilante who thwarts all of Panther Claw's evil schemes before disappearing. That cosplayer is Honey Kisaragi, the result of the late Professor Kisaragi's prize experiment. A master of disguise, Honey can magically alter her physical appearance and outfits. But with a push of the heart-shaped button on her choker, she transforms herself into Cutie Honey, the scantily-clad, sword-wielding warrior of love and justice. (Source: ANN)

With World War II right around the corner, intelligence on other countries' social and economic situation has become a valuable asset. As a result, Japan has established a new spy organization known as the "D Agency" to obtain this weapon. Under the command of Lieutenant Colonel Yuuki, eight agents have been assigned to infiltrate and observe some of the most powerful countries, reporting on any developments associated with the war. In order to carry out these dangerous tasks, these men have trained their bodies to survive in extreme conditions and studied numerous fields such as communications and languages. However, their greatest strength lies in their ability to manipulate people in order to obtain the information necessary to give their nation the upper hand. [Written by MAL Rewrite]

Having lost her mother at a young age, Misha Takanashi, a second grader who is half-Russian and half-Japanese, now lives with her Japanese father. Tsubame Kamoi, formerly a Japan Air Self-Defense Force, JASDF officer, comes to the Takanashi household as a housekeeper. This is a home comedy where Kamoi, a hardcore lolicon, attempts to get near Misha as she tries to fight against her.