Nagisa is a schoolgirl with schoolgirl tendencies, waking up late, rushing off to school and meeting up with friends upon the way. One morning Nagisa comes across a woman dressed in a strange uniform who seems to stare at her, unnerving Nagisa. Later that day, whilst staring out the window, Nagisa becomes aware of a ball bouncing by itself which flings itself towards her window seat, shattering the glass yet not harming her... Turning back to the front she finds a gaping mouth bristling with teeth inches from her face and no-one else about. She screams and the world returns to normal with her standing and the centre of curiosity of her class... why did she scream?

Delinquent Juu Juuzawa is a lone wolf who does not see much use in befriending people. So when a girl named Ame Ochibana claims they are linked together from their previous lives, he is highly skeptical and doesn't want anything to do with her. Even stranger is that her fondest wish is to be his servant. Thinking that Ame must be delusional, he tries to distance himself from her. But when a classmate is murdered, Juu instead decides to keep her close, believing the strange girl to be the culprit. However, her intelligence and skill begin to prove invaluable as the two begin working together to solve the murder. Denpa-teki na Kanojo weaves together a story of love, loss, and devotion, showing that allies can be found in the most unlikely of places.

The year is 21XX. Reploids are commonplace now, after Dr. Cain rediscovered Dr. Light's old lab and based several designs off of Dr.Light's original, called "Megaman X." X, meanwhile, has joined the Maverick Hunters, and works with unit leader Zero under the command of General Sigma. It is their job to terminate rogue reploids, those who have become violent.

The second part of the new Hokuto no Ken pentalogy. The story of this OVA centers around Yuria.