Due to his mother and sister, who both love professional wrestling, Kinjirou Sakamachi developed a resilient body that could take hard punches, aggressive kicks, and even deadly vehicle bumps, in order to survive their various grappling positions and locks. However, he also developed gynophobia, an abnormal fear of women. With just one touch from a girl, his nose bleeds uncontrollably, he sweats excessively, and in rare cases, faints abruptly. His life changes for the worse because of a fated meeting in the restroom. While trying to escape from a girl, he discovers that the most popular student in their school, Subaru Konoe—the butler of the headmaster’s daughter, Kanade Suzutsuki—is actually female! Surprised, Subaru violently assaults Kinjirou, dealing significant damage and knocking him unconscious. When he comes to, he meets Kanade. In exchange for his silence, she promises to help cure his phobia.

Satou has been in love with his childhood friend and neighbor, Hime, ever since she and her grandfather appeared out of nowhere 10 years ago. Now a dazzling, yet mysterious high school beauty, she makes it more and more difficult for him to confess his feelings. As the anniversary of their first meeting is nearing, will he muster up his courage to transform their friendship into something more? Or will an entirely different fate await this tightly bonded pair?

Tricked into assassinating his own prospective father-in-law, righteous samurai Raizou Kurima is overwhelmed with guilt. In order to reclaim his honor, Raizou swears vengeance on the lord who gave him those misleading orders. In his pursuit, he is aided by self-proclaimed merchant-of-all-trades Yuuen Usui, who is actually one of the Revengers—assassins who seek justice for the wronged and dispense bloody revenge on their behalf. Tragedy seems destined to follow Raizou as he becomes increasingly intertwined with members of the Revengers. As he begins working as a vigilante alongside them, the complicated web between the corrupt Japanese political elite, the unscrupulous Europeans, and the Revengers gradually reveals itself. The more entangled he becomes in these affairs, the more Raizou realizes that justice is as deceptive as the honor that he sought to redeem.

Vash the Stampede is the man with a $$60,000,000,000 bounty on his head. The reason: he's a merciless villain who lays waste to all those that oppose him and flattens entire cities for fun, garnering him the title "The Humanoid Typhoon." He leaves a trail of death and destruction wherever he goes, and anyone can count themselves dead if they so much as make eye contact—or so the rumors say. In actuality, Vash is a huge softie who claims to have never taken a life and avoids violence at all costs. With his crazy doughnut obsession and buffoonish attitude in tow, Vash traverses the wasteland of the planet Gunsmoke, all the while followed by two insurance agents, Meryl Stryfe and Milly Thompson, who attempt to minimize his impact on the public. But soon, their misadventures evolve into life-or-death situations as a group of legendary assassins are summoned to bring about suffering to the trio. Vash's agonizing past will be unraveled and his morality and principles pushed to the breaking point. [Written by MAL Rewrite]