While searching for a run-away cat the twins Riko and Rimu Mikogami find a strange device that transforms them into "Kirumin." It also enables them to turn into real animals. Their older sister Nagisa soon joins them. Now the three have cute, funny and sometimes dangerous adventures.

Fubuki Sakuragasaki is a powerful gamer who, with the power of her Passion Panties, climbs up the ranks of the BAG (Best of Arcade Gamer) tournament to become the greatest Arcade Gamer in the world. However, the evil Gulasic Group is out to conquer the world through said tournament, and their gaming skills will prove to be a challenge. Fubuki must team up with the legendary Mr. Mystery to combat the four Gods of Gaming and make the world of arcade gaming safe for all.

The anime will follow the adventures of Baron, a man living on continent of Arad in the year 981 after "the cursed light of Kazan" has fallen across the land. Thanks to the curse, one of his arms has become possessed. After finding a sword that has been possessed by the spirit Roxy, he embarks on a quest to unravel the secret of the curse and meets various people who also join his party.

Supersonic monkeys, vampires, talking fishmen, and all sorts of different supernatural monsters living alongside humans—this has been part of daily life in Hellsalem's Lot, formerly known as New York City, for some time now. When a gateway between Earth and the Beyond opened three years ago, New Yorkers and creatures from the other dimension alike were trapped in an impenetrable bubble and were forced to live together. Libra is a secret organization composed of eccentrics and superhumans, tasked with keeping order in the city and making sure that chaos doesn't spread to the rest of the world. Pursuing photography as a hobby, Leonardo Watch is living a normal life with his parents and sister. But when he obtains the "All-seeing Eyes of the Gods" at the expense of his sister's eyesight, he goes to Hellsalem's Lot in order to help her by finding answers about the mysterious powers he received. He soon runs into Libra, and when Leo unexpectedly joins their ranks, he gets more than what he bargained for. Kekkai Sensen follows Leo's misadventures in the strangest place on Earth with his equally strange comrades—as the ordinary boy unwittingly sees his life take a turn for the extraordinary.