Fam and Ihrie are willing to do almost anything to make a buck. So when these debt-driven damsels discover the potential profits to be hand in recovering a particularly dangerous mystical object, it means mortal peril for an entire civilization. There's no guarantee that they'll live long enough to squander the fabulous wealth they've been promised, and danger lurks around every turn as they cross dark seas in pursuit of legendary evil. Haunted by an unspeakable curse, plagued by doomsday prophecies, plotted against by untrustworthy traveling companions and looked in desperate race to gain the Ultimate Power, Fam and Ihrie are the Ruin Explorers!

Determined to pursue his glorious childhood dreams, 30-year-old Rick Gladiatol, a modest clerk in the adventurers' guild, is offered a once-in-a-lifetime opportunity after he fatefully encounters the dark elf Reanette Elfelt. Reanette happens to be an elite adventurer of the legendary party Orichalcum Fist, whose members welcome Rick under the condition that he follow a Spartan training. Two years later, Rick is finally ready to take the E-Rank exam officially qualifying him as an adventurer. However, raw magical power can only be developed until one turns 20. As such, Rick faces the general hostility of fellow participants and examiners alike, leaving him no choice but to show the world that his hellish training has turned him into an invincible warrior.

Sasahara Natsuki is a poor bounty hunter in a world where monsters and humans live together. Most of her cases involve monsters infringing upon the rights of humans, who are protected by law from their generally more powerful neighbors. Being half-human and half cat-beast, Natsuki straddles the two societies and tries to understand and respect both while enforcing the law. She is assisted by a werewolf named Batanen who is afraid to admit he loves her; another werewolf named Tommy; and a Kyubi fox demon named Sakura who has her own plans--which include eating Natsuki to complete her her nine tails and thereby her magical powers.

Once every century, the legendary mahjong dials called the "Legendary Pai" show themselves to the world, and if you collect them all it will grant you any wish. They show up in the form of evil monsters and you must defeat all 10 to obtain this chance. So, a Bunny Alien, A Maid-Dominatrix, A Cyborg, A girl form the world of magic and a transforming super hero all must fight these monsters along with themselves to grant the wish that they want to come true.