D.S.O. agent Leon S. Kennedy is on a mission to rescue Dr. Antonio Taylor from kidnappers, when a mysterious woman thwarts his pursuit. Meanwhile, B.S.A.A. agent Chris Redfield is investigating a zombie outbreak in San Francisco, where the cause of the infection cannot be identified. The only thing the victims have in common is that they all visited Alcatraz Island recently. Following that clue, Chris and his team head to the island, where a new horror awaits them.

A behind the scenes special of all the main characters in Amaenaide yo!! Katsu!!, where they give their own personal feelings about their past experiences with the show, as well as their working experiences with their fellow cast members.

With the completion of the Summer Troupe's show, Izumi Tachibana must now recruit five members for the next sub-troupe, the Autumn Troupe. Luckily, enough people arrive at the audition: Banri Settsu, a talented but boastful jack of all trades; Juuza Hyoudou, a stone-faced delinquent passionate about acting; Taichi Nanao, a man wanting to impress girls through the stage; Omi Fushimi, a college student, amateur photographer, and adept cook; and Sakyou Furuichi, a yakuza member who shares a past connection with the Mankai Company. But between the non-existent teamwork and multiple threats jeopardizing the show's success, Izumi realizes that the troupe might be more difficult to handle than she first thought. How will she be able to unite them in time for their debut performance?

Kyouhei, after moving away to Tokyo from his old town to get away from the events that happened, is on a goukon with his friends, including his old neighbor, Shiba. After drinking for a whole night, he and Shiba discover a dead, bloody body in the elevator. He is told by his younger sister, Utao with her Kamisama Doll, that Aki, an old friend, and his Doll are the culprits responsible.