Adaptation of Takashi Noguchi's manga, which itself adapts Baku Yumemakura's supernatural romance novel. The original novel is about a 12th-century man named Minamoto no Yoshitsune (Kurou). Kurou flees into the mountains after losing to his brother Minamoto no Yoritomo, the first Shogun to rule all of Japan. History records that he committed suicide, but instead, Kurou meets a strange, beautiful woman named Kuromitsu in her mountain hermitage. Eventually, Kurou falls in love with Kuromitsu, but then realizes she conceals a dark secret. He learns that he is unable to die and continues to live for a thousand years as Japan evolves into a future society.

At the onset of World War III, nobody could have predicted the effect it would have on Japan. While it had officially ended fifty years ago in 2150, its battles still persist. Large, mysterious areas known as "Blackspots" appeared across the country, filled with the contaminated ruins of cities and countrysides. Those inside were trapped to halt the spread of contamination, and their powers began to mutate—be they shapeshifters, pyromancers, or controllers of gravity itself—they all became known as the Needless. Adam Blade is one such Needless, possessing remarkable regenerative abilities and incredible strength. In order to restore peace to a war-torn Japan, he and his allies must fight together to rise against a heinous research group by the name of Simeon.

Yoshihito, a 23-year-old man who has no job or girlfriend. In order to make ends meet he rents out one of the rooms in his house. While he's showing Lily, his first tenant, around the house, she's suddenly attacked by a vampire named Vivian, and Yoshihito notices that Lily is actually a werewolf. As Yoshihito and Lily start living in the same house, Yoshihito is scouted for an organization that maintains order of the parallel universes, and strange creatures one after another become tenants in his house. (Source: ANN)

At first glance, Galko, Otako, and Ojou are three high school girls who seem like they wouldn’t have anything to do with each other. Galko is a social butterfly with a reputation for being a party animal, even though she is actually innocent and good-hearted despite her appearance. Otako is a plain-looking girl with a sarcastic personality and a rabid love of manga. And Ojou is a wealthy young lady with excellent social graces, though she can be a bit absent-minded at times. Despite their differences, the three are best friends, and together they love to talk about various myths and ask candid questions about the female body. Oshiete! Galko-chan is a lighthearted and humorous look at three very different girls and their frank conversations about themselves and everyday life. No topic is too safe or too sensitive for them to joke about—even though every so often, Galko seems to get a bit embarrassed by their discussions! [Written by MAL Rewrite]