A stubborn girl on a mysterious island, her dreams of becoming a martial artist, and her complicated love story.

Otaku Kunoichi ≒ Otaku NEET ≒ Girl with Zero Romantic Experience! A normal salaryman, Tsukasa, is attacked by a Youma and is gallantly saved by the appearance of the genius kunoichi, Shizuri. However, when she is not working, she becomes an otaku NEET... Today, Tsukasa's househusband skills will continue to spoil Shizuri. A prescription delivered directly to you♪

In Tenikai General Hospital's general diagnostic department, patients who are deemed difficult to treat by other doctors are collected here. From mysteries of unknown illness to murders that even the police can't handle. Genius doctor Takao Ameku reveals the shocking truth hidden behind these mysterious "disease."