The story follows Iruma Suzuki, a 14-year-old human boy, who is sold to a demon by his parents. The demon, known as Sullivan, takes Iruma to the Demon World and officially adopts him as his grandson. He enrolls Iruma in the Babyls School for Demons where he is the headmaster and where Iruma quickly befriends the demons Alice Asmodeus and Clara Valac. However, Sullivan tells Iruma to never reveal that he is human since he will be eaten if anyone finds out. Iruma then vows to blend in during his time in the demon world, although he only stands out because of all the situations and adventures that arise.

Tomoya Okazaki is a delinquent who finds life dull and believes he'll never amount to anything. Along with his friend Youhei Sunohara, he skips school and plans to waste his high school days away. One day while walking to school, Tomoya passes a young girl muttering quietly to herself. Without warning she exclaims "Anpan!" (a popular Japanese food) which catches Tomoya's attention. He soon discovers the girl's name is Nagisa Furukawa and that she exclaims things she likes in order to motivate herself. Nagisa claims they are now friends, but Tomoya walks away passing the encounter off as nothing. However, Tomoya finds he is noticing Nagisa more and more around school. Eventually he concedes and befriends her. Tomoya learns Nagisa has been held back a year due to a severe illness and that her dream is to revive the school's drama club. Claiming he has nothing better to do, he decides to help her achieve this goal along with the help of four other girls. As Tomoya spends more time with the girls, he learns more about them and their problems. As he attempts to help each girl overcome her respective obstacle, he begins to realize life isn't as dull as he once thought. [Written by MAL Rewrite]

Touta Konoe is an ordinary boy raised in a small rural town. His mundane life suddenly changes when his mentor, Katherine McDowell, reveals herself to be a vampire; after saving Touta from a mortal wound, she causes him to become immortal as well. Already yearning to explore the world, young Touta finally puts his dream to ascend to the top of Amanomihashira—a tower that leads to outer space—into realization. Along the way, he finds a secret society filled with immortals just like him called "UQ Holders." Gaining new comrades and mentorship along the way, Touta embarks on his own unique, magical adventure. [Written by MAL Rewrite]

Rishe Irmgard Weitzner finds herself in a familiar situation: her fiancé is publicly breaking off their engagement, and her ducal family is about to disown her in shame. However, Rishe is not distraught; she has already had six chances to rebuild her life and chase a different passion each time. But she would always get swept up in a war and die, so now she wishes for her seventh reincarnation to be easygoing and uneventful. What Rishe does not take into account is the presence of Arnold Hein, the crown prince of the Galkhein Kingdom. He is destined to usurp the throne and become a tyrant who starts a large-scale invasion of neighboring countries. To make their encounter worse, Arnold is the one who killed Rishe in her previous life. That is why it is all the more shocking when he proposes to Rishe on the spot. In pursuit of her desired life, Rishe must consider accepting Arnold's proposal and discover the reasons behind his brutal actions to stop the war from ever happening.