Many of us know what it is like to transition to a new school with few to no friends in a new environment, going through the arduous process of getting to know people again. Bocchi Hitori knows this struggle all too well, having just graduated from elementary school and thrown into middle school. Unfortunately, she suffers from extreme social anxiety: she faints when overwhelmed, vomits when nervous, and draws up ridiculously convoluted plans to avoid social contact. It does not help that her only friend from elementary school, Kai Yawara, will not be attending the same middle school as Bocchi. However, wanting to help her, Kai severs ties with Bocchi and promises to reconcile with her when she befriends all of her classmates in her new middle school class. Even though Bocchi has no faith in herself, she is determined to be friends with Kai again. Summoning all of her courage, Bocchi takes on the daunting challenge of making friends with her entire class, starting with the delinquent-looking girl sitting in front of her... [Written by MAL Rewrite]

Based on mystery novels written by Mochizuki Mai. There is an antique shop in Kyoto's Teramachi Sanjou shopping district. High school girl Mashiro Aoi unexpectedly runs into Yagashira Kiyotaka, the son of the shop's owner, and ends up working part-time at the shop. Kiyotaka is called the "Holmes at Teramachi Sanjou," and he and Aoi solve odd cases brought to them by various clients. (Source: ANN)

On the surface, the thought of Kyouko Hori and Izumi Miyamura getting along would be the last thing in people's minds. After all, Hori has a perfect combination of beauty and brains, while Miyamura appears meek and distant to his fellow classmates. However, a fateful meeting between the two lays both of their hidden selves bare. Even though she is popular at school, Hori has little time to socialize with her friends due to housework. On the other hand, Miyamura lives under the noses of his peers, his body bearing secret tattoos and piercings that make him look like a gentle delinquent. Having opposite personalities yet sharing odd similarities, the two quickly become friends and often spend time together in Hori's home. As they both emerge from their shells, they share with each other a side of themselves concealed from the outside world. [Written by MAL Rewrite]

Effeminate fifth grader Shuuichi Nitori is considered by most to be one of the prettiest girls in school, but much to her dismay, she is actually biologically male. Fortunately, Shuuichi has a childhood friend who has similar feelings of discomfort related to gender identity: the lanky tomboy Yoshino Takatsuki, who, though biologically female, does not identify as a girl. These two friends share a similar secret and find solace in one another; however, their lives become even more complicated when they must tread the unfamiliar waters of a new school, attempt to make new friends, and struggle to maintain old ones. Faced with nearly insurmountable odds, they must learn to deal with the harsh realities of growing up, transexuality, relationships, and acceptance. Lauded as a decidedly serious take on gender identity and LGBT struggles, Takako Shimura's Hourou Musuko is about Shuuichi and Yoshino's attempts to discover their true selves as they enter puberty, make friends, fall in love, and face some very real and difficult choices. [Written by MAL Rewrite]