With a cartload of fur pelts in tow, traveling merchant Kraft Lawrence stops by the village of Pasloe. According to local folklore, centuries ago, one of the villagers made a promise with the wolf deity Holo, who swore to bless Pasloe with bountiful harvests of wheat. Yet, as time passed, such stories became little more than relics of the past. After quickly finishing his business in the village, Lawrence sets out to his next destination. His journey, however, takes an unexpected turn when he discovers a nude, animal-eared girl sleeping among his pelts. Even more surprisingly, the youthful-looking woman claims to be Holo—the wolf of legend. Holo wishes to return to her hometown in the north, and though their first encounter is rocky, she convinces Lawrence to accompany her on her travels. In return, she vows to earn her keep, using her quick wits and lifetime of experience to help her newfound companion in his dealings. As they continue their journey, Lawrence and Holo take advantage of whatever economic opportunities they come across, often landing in situations that put both their business skills and their relationship to the test.

Determined to pursue his glorious childhood dreams, 30-year-old Rick Gladiatol, a modest clerk in the adventurers' guild, is offered a once-in-a-lifetime opportunity after he fatefully encounters the dark elf Reanette Elfelt. Reanette happens to be an elite adventurer of the legendary party Orichalcum Fist, whose members welcome Rick under the condition that he follow a Spartan training. Two years later, Rick is finally ready to take the E-Rank exam officially qualifying him as an adventurer. However, raw magical power can only be developed until one turns 20. As such, Rick faces the general hostility of fellow participants and examiners alike, leaving him no choice but to show the world that his hellish training has turned him into an invincible warrior.

An adventure in another world with cute girls by your side and video game-like powers—sounds like an anime fan's dream, right? Not so for melancholic author Osamu Dazai, who would quite literally prefer to drop dead. Video games haven't even been invented yet when he gets yanked into another world in 1948. Really, all the fantastical adventure he keeps running into is just getting in the way of his poetic dream of finding the perfect place to die. But no matter how much he risks his hide, everything seems to keep turning out okay. Follow a miserable hero like no other in this cheerfully bleak isekai comedy!

Aspiring samurai Shinsuke Hyoudou's world is turned upside down when he witnesses hermit Jinka Yamato and fox girl Tama Youko slay a brigands' lair in the blink of an eye. Tama happens to be katawara, a magically gifted species, who can share her powers with Jinka through a special ritual. Together, they travel the world as vigilantes to stop evil beings, be they katawara or human. As Shinsuke learns more about this new world, he discovers that monks perform inhumane research on spiritually gifted civilians, in the hope of creating human-katawara hybrids that can fight against monsters. Soon joined by Shakuyaku—a girl they manage to save from the monks’ experiments—and other allies, the group embarks on a quest to achieve their respective dreams.