Part-time peddler, part-time alchemist working under Comte de Saint-Germain, his real name is Giuseppe Balsamo and was first seen selling perfumes in Russia. A rather aloof and debaucherous man, Cagliostro has acquired a taste for fine liquor wherever he goes. He describes his life as a "comedy on stage," and tells Lorenza that he will create "a high class tragedy" instead.

Later he switches alliances, betraying Saint-Germain and working for Maximillien. At the anime series' end, when Robin takes up Maximillien's name to lead a revolution, he is seen standing behind him.